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Gene Transfer with Poly-Melittin Peptides

The 26 amino acid hemolytic melittin peptide was converted into a gene transfer peptide that binds to DNA and polymerized through disulfide bond formation. Melittin analogues were synthesized by addition of one to four Lys repeats at either the C or N-subterminal end along with terminal Cys residues...

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Autores principales: Chen, Chang-Po, Kim, Ji-seon, Steenblock, Erin, Liu, Dijie, Rice, Kevin G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533530/
https://ncbi.nlm.nih.gov/pubmed/16848415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060028l
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