Human dopamine beta-hydroxylase (DBH) regulatory polymorphism that influences enzymatic activity, autonomic function, and blood pressure

RATIONALE: Dopamine beta-hydroxylase (DBH) plays an essential role in catecholamine synthesis by converting dopamine into norepinephrine. Here we systematically investigated DBH polymorphisms associated with enzymatic activity as well as autonomic and BP/disease phenotypes in vivo. METHODS AND RESUL...

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Autori principali: Chen, Yuqing, Wen, Gen, Rao, Fangwen, Zhang, Kuixing, Wang, Lei, Rodriguez-Flores, Juan L., Sanchez, Amber P., Mahata, Manjula, Taupenot, Laurent, Sun, Ping, Mahata, Sushil K., Tayo, Bamidele, Schork, Nicholas J., Ziegler, Michael G., Hamilton, Bruce A., O'Connor, Daniel T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860271/
https://ncbi.nlm.nih.gov/pubmed/20009769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e328332bc87
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