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Acyl radical insertion for the direct formation of new 7-substituted pterin analogs

A variety of pterin molecules were synthesized via an under-utilized acyl radical insertion, using aldehydes and α-keto esters as the acyl source. These reactions gave complete regiospecificity for the 7-isomer, with reaction times ranging in minutes, often with instantaneous product precipitation....

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Detalhes bibliográficos
Main Authors: Pruet, Jeff M., Robertus, Jon D., Anslyn, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860152/
https://ncbi.nlm.nih.gov/pubmed/20436939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.03.008
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