Polymorphisms in the Pseudomonas aeruginosa Type III secretion protein, PcrV - implications for anti-PcrV Immunotherapy

The type III secretion system of P. aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglo...

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Main Authors: Lynch, Susan V., Flanagan, Judith L., Sawa, Teiji, Fang, Alice, Baek, Marshall S., Rubio-Mills, Amua, Ajayi, Temitayo, Yanagihara, Katsunori, Hirakata, Yoichi, Kohno, Shigeru, Misset, Benoit, Nguyen, Jean-Claude, Wiener-Kronish, Jeanine P.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860055/
https://ncbi.nlm.nih.gov/pubmed/20211240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.02.008
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