Polymorphisms in the Pseudomonas aeruginosa Type III secretion protein, PcrV - implications for anti-PcrV Immunotherapy

The type III secretion system of P. aeruginosa, responsible for acute infection, is composed of over twenty proteins that facilitate cytotoxin injection directly into host cells. Integral to this process is production and secretion of PcrV. Administration of a recently developed, anti-PcrV immunoglo...

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Detalhes bibliográficos
Main Authors: Lynch, Susan V., Flanagan, Judith L., Sawa, Teiji, Fang, Alice, Baek, Marshall S., Rubio-Mills, Amua, Ajayi, Temitayo, Yanagihara, Katsunori, Hirakata, Yoichi, Kohno, Shigeru, Misset, Benoit, Nguyen, Jean-Claude, Wiener-Kronish, Jeanine P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860055/
https://ncbi.nlm.nih.gov/pubmed/20211240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2010.02.008
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