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Review: Autophagy and neurodegeneration: survival at a cost?
Protein aggregation, mitochondrial impairment and oxidative stress are common to multiple neurodegenerative diseases. Homeostasis is regulated by a balanced set of anabolic and catabolic responses, which govern removal and repair of damaged proteins and organelles. Macroautophagy is an evolutionaril...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860012/ https://ncbi.nlm.nih.gov/pubmed/20202120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2990.2010.01062.x |
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