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Autophagy in neuroprotection and neurodegeneration: A question of balance

A central issue in developing therapies for neurodegenerative diseases involves understanding why adaptive responses to stress or injury fail to prevent synaptic dysfunction and neuronal cell death. Macroautophagy is a major, evolutionarily conserved response to nutrient and bioenergetic stresses, w...

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Autors principals: Cherra, Salvatore J., Chu, Charleen T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544613/
https://ncbi.nlm.nih.gov/pubmed/18806889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796708.3.3.309
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