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Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 Deoxy- Δ(12,14) - Prostaglandin J(2)
Arachidonic acid derived endogenous electrophile 15d-PGJ2 has gained much attention in recent years due to its potent anti-proliferative and anti-inflammatory actions mediated through thiol modification of cysteine residues in its target proteins. Here, we show that 15d-PGJ2 at 1µM concentration con...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859997/ https://ncbi.nlm.nih.gov/pubmed/20307494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.03.093 |
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