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Short biodegradable polyamines for gene delivery and transfection of brain capillary endothelial cells

With the goal of rational design of systemic gene delivery system and efficient transfection of capillary endothelial cells forming the blood-brain barrier (BBB), we synthesized several short polyamines with reducible disulfide backbones for pDNA packaging, internalization and consequent release fro...

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Autori principali: Zhang, Hongwei, Vinogradov, Serguei V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859984/
https://ncbi.nlm.nih.gov/pubmed/20093156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.01.020
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