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Nanogels for Oligonucleotide Delivery to the Brain

Systemic delivery of oligonucleotides (ODN) to the central nervous system is needed for development of therapeutic and diagnostic modalities for treatment of neurodegenerative disorders. Macromolecules injected in blood are poorly transported across the blood–brain barrier (BBB) and rapidly cleared...

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Detalles Bibliográficos
Main Authors: Vinogradov, Serguei V., Batrakova, Elena V., Kabanov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837941/
https://ncbi.nlm.nih.gov/pubmed/14733583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc034164r
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