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Multifunctional Peptide-PEG Intercalating Conjugates: Programmatic of Gene Delivery to the Blood-Brain Barrier
PURPOSE: To enhance transfection efficacy of pDNA through the application of multifunctional peptide-PEG-tris-acridine conjugates (pPAC) and the formation of biodegradable core-shell polyplexes for gene delivery to the blood-brain barrier (BBB). METHODS: pPAC-mediated transfection was compositionall...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998179/ https://ncbi.nlm.nih.gov/pubmed/20824308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0256-x |
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