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Conjugation of peptides to short-acyl-chain ceramides for delivery across mucosal cell barriers
Robust transport of therapeutic peptides and other medicinal molecules across tight epithelial barriers would overcome the major obstacle to oral delivery. We have already demonstrated that peptides conjugated to gangliosides (GM1 and GM3) having non-native short N-acyl groups hijack the endogenous...
में बचाया:
| में प्रकाशित: | Bioorg Med Chem Lett |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7174066/ https://ncbi.nlm.nih.gov/pubmed/32081448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2020.127014 |
| टैग : |
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