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Efficient Nuclear Targeting by NLS-PEG-Acridine Conjugates in the Transfection of Blood-Brain Barrier Endothelial Cells with Lipoplexes and Polyplexes
Brain capillary endothelial cells of the blood brain barrier (BBB) are difficult target for non-viral transfection even for most potent transfection agents. Efficient protection and nuclear delivery of plasmid DNA are the key requirements for enhancing the transfection. We designed novel DNA interca...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2744408/ https://ncbi.nlm.nih.gov/pubmed/19067581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8003414 |
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