Inflammation Driven by Overexpression of the Hypoglycosylated Abnormal MUC1 Links Inflammatory Bowel Disease (IBD) and Pancreatitis

OBJECTIVES: Pancreatitis occurs as extraintestinal complication of IBD but the cause is poorly understood. MUC1 is overexpressed in an abnormal, hypoglycosylated form on the colonic epithelium in human IBD where it contributes to inflammation. MUC1 is also expressed on pancreatic ductal epithelia. W...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kadayakkara, Deepak K., Beatty, Pamela L., Turner, Michael S., Janjic, Jelena M., Ahrens, Eric T., Finn, Olivera J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859977/
https://ncbi.nlm.nih.gov/pubmed/20084048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181bd6501
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