Inflammation Driven by Overexpression of the Hypoglycosylated Abnormal MUC1 Links Inflammatory Bowel Disease (IBD) and Pancreatitis

OBJECTIVES: Pancreatitis occurs as extraintestinal complication of IBD but the cause is poorly understood. MUC1 is overexpressed in an abnormal, hypoglycosylated form on the colonic epithelium in human IBD where it contributes to inflammation. MUC1 is also expressed on pancreatic ductal epithelia. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Kadayakkara, Deepak K., Beatty, Pamela L., Turner, Michael S., Janjic, Jelena M., Ahrens, Eric T., Finn, Olivera J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859977/
https://ncbi.nlm.nih.gov/pubmed/20084048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e3181bd6501
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