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Humoral immune response to abnormal MUC1 in subjects with colorectal adenoma and cancer

Colorectal cancer (CRC) expresses a hypoglycosylated (abnormal) form of MUC1 different than MUC1 expressed in normal colon, which elicits antibodies in patients with CRC. This form of MUC1 is expressed in other abnormal but non-malignant lesions in the colon, such as adenomatous polyps, precursors t...

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Detalhes bibliográficos
Main Authors: Silk, Ann Willman, Schoen, Robert E., Potter, Douglas M., Finn, Olivera J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789300/
https://ncbi.nlm.nih.gov/pubmed/19217667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.12.025
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