The receptor interacting protein (RIP1) inhibits p53 induction through NF-κB activation and confers a worse prognosis in glioblastoma

NF-κB activation may play an important role in the pathogenesis of cancer and also in resistance to treatment. Inactivation of the p53 tumor suppressor is a key component of the multi-step evolution of most cancers. Links between the NF-κB and p53 pathways are under intense investigation. In this st...

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Detalhes bibliográficos
Main Authors: Park, Seongmi, Hatanpaa, Kimmo J., Xie, Yang, Mickey, Bruce E., Madden, Christopher J., Raisanen, Jack M., Ramnarain, Deepti B., Xiao, Guanghua, Saha, Debabrata, Boothman, David A., Zhao, Dawen, Bachoo, Robert M., Pieper, Russell O., Habib, Amyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859885/
https://ncbi.nlm.nih.gov/pubmed/19339267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4079
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