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Cdk5 Nuclear Localization Is p27-dependent in Nerve Cells: IMPLICATIONS FOR CELL CYCLE SUPPRESSION AND CASPASE-3 ACTIVATION
Initiation of a cell cycle in an adult neuron leads to cell death, placing great importance on the mechanisms that normally suppress the neuronal cell cycle. We have previously shown that the cyclin-dependent kinase Cdk5 is an important part of this process, but only when it is present in the nucleu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859566/ https://ncbi.nlm.nih.gov/pubmed/20189989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068262 |
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