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AMSH Interacts with ESCRT-0 to Regulate the Stability and Trafficking of CXCR4

Reversible ubiquitination is essential for the endocytic sorting and down-regulation of G protein-coupled receptors, such as the chemokine receptor CXCR4. The deubiquitinating enzyme AMSH has been implicated in the endocytic sorting of both G protein-coupled receptors and receptor-tyrosine kinases....

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Hlavní autoři: Sierra, Maria I., Wright, Michelle H., Nash, Piers D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859561/
https://ncbi.nlm.nih.gov/pubmed/20159979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061309
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