AMSH Interacts with ESCRT-0 to Regulate the Stability and Trafficking of CXCR4

Reversible ubiquitination is essential for the endocytic sorting and down-regulation of G protein-coupled receptors, such as the chemokine receptor CXCR4. The deubiquitinating enzyme AMSH has been implicated in the endocytic sorting of both G protein-coupled receptors and receptor-tyrosine kinases....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sierra, Maria I., Wright, Michelle H., Nash, Piers D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859561/
https://ncbi.nlm.nih.gov/pubmed/20159979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061309
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