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Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy
PURPOSE: Aberrant expression of inflammatory molecules, such as inducible nitric oxide synthase (iNOS), has been linked to cancer, suggesting that their inhibition is a rational therapeutic approach. While iNOS expression in melanoma and other cancers is associated with poor clinical prognosis, in v...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858983/ https://ncbi.nlm.nih.gov/pubmed/20215556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-3123 |
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