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Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Genetically encoded calcium indicators (GECIs) can be used to image activity in defined neuronal populations. However, current GECIs produce inferior signals compared to synthetic indicators and recording electrodes, precluding detection of low firing rates. We developed a single-wavelength GECI bas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tian, Lin, Hires, S. Andrew, Mao, Tianyi, Huber, Daniel, Chiappe, M. Eugenia, Chalasani, Sreekanth H., Petreanu, Leopoldo, Akerboom, Jasper, McKinney, Sean A., Schreiter, Eric R., Bargmann, Cornelia I., Jayaraman, Vivek, Svoboda, Karel, Looger, Loren L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858873/
https://ncbi.nlm.nih.gov/pubmed/19898485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1398
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