Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience. Recent efforts in protein engineering have significantly increased the performance of GECIs. The state-of-the art single-wavelength GECI, GCaMP3, has been deployed in a number of model organisms and can relia...

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Αποθηκεύτηκε σε:
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Κύριοι συγγραφείς: Akerboom, Jasper, Chen, Tsai-Wen, Wardill, Trevor J., Tian, Lin, Marvin, Jonathan S., Mutlu, Sevinç, Calderón, Nicole Carreras, Esposti, Federico, Borghuis, Bart G., Sun, Xiaonan Richard, Gordus, Andrew, Orger, Michael B., Portugues, Ruben, Engert, Florian, Macklin, John J., Filosa, Alessandro, Aggarwal, Aman, Kerr, Rex A., Takagi, Ryousuke, Kracun, Sebastian, Shigetomi, Eiji, Khakh, Baljit S., Baier, Herwig, Lagnado, Leon, Wang, Samuel S.-H., Bargmann, Cornelia I., Kimmel, Bruce E., Jayaraman, Vivek, Svoboda, Karel, Kim, Douglas S., Schreiter, Eric R., Looger, Loren L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Society for Neuroscience 2012
Θέματα:
Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482105/
https://ncbi.nlm.nih.gov/pubmed/23035093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2601-12.2012
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