Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience. Recent efforts in protein engineering have significantly increased the performance of GECIs. The state-of-the art single-wavelength GECI, GCaMP3, has been deployed in a number of model organisms and can relia...

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主要な著者: Akerboom, Jasper, Chen, Tsai-Wen, Wardill, Trevor J., Tian, Lin, Marvin, Jonathan S., Mutlu, Sevinç, Calderón, Nicole Carreras, Esposti, Federico, Borghuis, Bart G., Sun, Xiaonan Richard, Gordus, Andrew, Orger, Michael B., Portugues, Ruben, Engert, Florian, Macklin, John J., Filosa, Alessandro, Aggarwal, Aman, Kerr, Rex A., Takagi, Ryousuke, Kracun, Sebastian, Shigetomi, Eiji, Khakh, Baljit S., Baier, Herwig, Lagnado, Leon, Wang, Samuel S.-H., Bargmann, Cornelia I., Kimmel, Bruce E., Jayaraman, Vivek, Svoboda, Karel, Kim, Douglas S., Schreiter, Eric R., Looger, Loren L.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2012
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Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482105/
https://ncbi.nlm.nih.gov/pubmed/23035093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2601-12.2012
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