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Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells

BACKGROUND: Endogenously produced interferons can regulate the growth of melanoma cells and are administered exogenously as therapeutic agents to patients with advanced cancer. We investigated the role of negative regulators of interferon signaling known as suppressors of cytokine signaling (SOCS) i...

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Bibliographische Detailangaben
Hauptverfasser: Lesinski, Gregory B, Zimmerer, Jason M, Kreiner, Melanie, Trefry, John, Bill, Matthew A, Young, Gregory S, Becknell, Brian, Carson, William E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858748/
https://ncbi.nlm.nih.gov/pubmed/20398276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-142
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