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Gene Expression Profiling Reveals Similarities between the In vitro and In vivo Responses of Immune Effector Cells to Interferon-Alpha
PURPOSE: The precise molecular targets of interferon-alpha (IFN-α) therapy in the context of malignant melanoma are unknown but appear to involve STAT1 signal transduction within host immune effector cells. We hypothesized that the in vitro transcriptional response of patient PBMCs to IFN-α would be...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762274/ https://ncbi.nlm.nih.gov/pubmed/18794103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0846 |
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