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Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells

BACKGROUND: Endogenously produced interferons can regulate the growth of melanoma cells and are administered exogenously as therapeutic agents to patients with advanced cancer. We investigated the role of negative regulators of interferon signaling known as suppressors of cytokine signaling (SOCS) i...

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Detalhes bibliográficos
Main Authors: Lesinski, Gregory B, Zimmerer, Jason M, Kreiner, Melanie, Trefry, John, Bill, Matthew A, Young, Gregory S, Becknell, Brian, Carson, William E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858748/
https://ncbi.nlm.nih.gov/pubmed/20398276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-142
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