Gene Expression Profiling Reveals Similarities between the In vitro and In vivo Responses of Immune Effector Cells to Interferon-Alpha

PURPOSE: The precise molecular targets of interferon-alpha (IFN-α) therapy in the context of malignant melanoma are unknown but appear to involve STAT1 signal transduction within host immune effector cells. We hypothesized that the in vitro transcriptional response of patient PBMCs to IFN-α would be...

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Hlavní autoři: Zimmerer, Jason M., Lesinski, Gregory B., Ruppert, Amy S., Radmacher, Michael D., Noble, Carl, Kendra, Kari, Walker, Michael J., Carson, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762274/
https://ncbi.nlm.nih.gov/pubmed/18794103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0846
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