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Synaptic Mechanism for Functional Synergism between δ- and μ-Opioid Receptors

By sustained activation of μ-opioid receptors (MORs), chronic opioids cause analgesic tolerance, physical dependence, and opioid addiction, common clinical problems for which an effective treatment is still lacking. Chronic opioids recruit δ-opioid receptors (DORs) to plasma membrane through exocyto...

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Detalhes bibliográficos
Main Authors: Zhang, Zhi, Pan, Zhizhong Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858689/
https://ncbi.nlm.nih.gov/pubmed/20357124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5968-09.2010
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