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Interaction and regulatory functions of μ- and δ-opioid receptors in nociceptive afferent neurons

μ-opioid receptor (MOR) agonists such as morphine are powerful analgesics used for pain therapy. However, the use of these drugs is limited by their side-effects, which include antinociceptive tolerance and dependence. Earlier studies reported that MOR analgesic tolerance is reduced by blockade of δ...

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Библиографические подробности
Опубликовано в: :Neurosci Bull
Главные авторы: Zhang, Xu, Bao, Lan
Формат: Artigo
Язык:Inglês
Опубликовано: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560394/
https://ncbi.nlm.nih.gov/pubmed/22466123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1206-x
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