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Interaction and regulatory functions of μ- and δ-opioid receptors in nociceptive afferent neurons
μ-opioid receptor (MOR) agonists such as morphine are powerful analgesics used for pain therapy. However, the use of these drugs is limited by their side-effects, which include antinociceptive tolerance and dependence. Earlier studies reported that MOR analgesic tolerance is reduced by blockade of δ...
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Publicado no: | Neurosci Bull |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560394/ https://ncbi.nlm.nih.gov/pubmed/22466123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1206-x |
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