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Synaptic Mechanism for Functional Synergism between δ- and μ-Opioid Receptors
By sustained activation of μ-opioid receptors (MORs), chronic opioids cause analgesic tolerance, physical dependence, and opioid addiction, common clinical problems for which an effective treatment is still lacking. Chronic opioids recruit δ-opioid receptors (DORs) to plasma membrane through exocyto...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858689/ https://ncbi.nlm.nih.gov/pubmed/20357124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5968-09.2010 |
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