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αB-crystallin regulation of angiogenesis by modulation of VEGF

αB-crystallin is a chaperone belonging to the small heat shock protein family. Herein we show attenuation of intraocular angiogenesis in αB-crystallin knockout (αB-crystallin(−/−)) mice in 2 models of intraocular disease: oxygen-induced retinopathy and laser-induced choroidal neovascularization. Vas...

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Detalhes bibliográficos
Main Authors: Kase, Satoru, He, Shikun, Sonoda, Shozo, Kitamura, Mizuki, Spee, Christine, Wawrousek, Eric, Ryan, Stephen J., Kannan, Ram, Hinton, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858494/
https://ncbi.nlm.nih.gov/pubmed/20023214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-197095
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