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Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9
Bone morphorgenetic protein (BMP)-4 has been shown to play a pivotal role in eye development; however, its role in mature retina or ocular angiogenic diseases is unclear. Activating downstream Smad signaling, BMP4 can be either pro-angiogenic or anti-angiogenic, depending on the context of cell type...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413482/ https://ncbi.nlm.nih.gov/pubmed/22392094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9254-4 |
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