α-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

PURPOSE: To investigate the susceptibility of retinal pigment epithelium (RPE) from αA (-/-) and αB (-/-) mice to oxidative stress, and the subcellular changes of αA and αB-crystallins under oxidative stress. METHODS: The effect of hydrogen peroxide (H(2)O(2)) on apoptosis in RPE from αA (-/-), αB (...

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Main Authors: Yaung, Jennifer, Jin, Manlin, Barron, Ernesto, Spee, Christine, Wawrousek, Eric F., Kannan, Ram, Hinton, David R.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2007
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652021/
https://ncbi.nlm.nih.gov/pubmed/17438522
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