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Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

This study evaluated the role of crystallins in retinal degeneration induced by chemical hypoxia. Wild type, αA-crystallin (−/−), and αB-crystallin (−/−) mice received intravitreal injection of 12 nmol (low dose), 33 nmol (intermediate dose) or 60 nmol (high dose) cobalt chloride (CoCl(2)). Hematoxy...

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Detalhes bibliográficos
Main Authors: Yaung, Jennifer, Kannan, Ram, Wawrousek, Eric F., Spee, Christine, Sreekumar, Parameswaran G., Hinton, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731668/
https://ncbi.nlm.nih.gov/pubmed/18191123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.11.007
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