Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

This study evaluated the role of crystallins in retinal degeneration induced by chemical hypoxia. Wild type, αA-crystallin (−/−), and αB-crystallin (−/−) mice received intravitreal injection of 12 nmol (low dose), 33 nmol (intermediate dose) or 60 nmol (high dose) cobalt chloride (CoCl(2)). Hematoxy...

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Bibliographic Details
Main Authors: Yaung, Jennifer, Kannan, Ram, Wawrousek, Eric F., Spee, Christine, Sreekumar, Parameswaran G., Hinton, David R.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731668/
https://ncbi.nlm.nih.gov/pubmed/18191123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.11.007
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