Deficient Gadd45β in rheumatoid arthritis: Enhanced synovitis through JNK signaling

OBJECTIVE: c-Jun-N-terminal kinase (JNK)-mediated cell signaling plays a critical role in metalloproteinase (MMP) expression and joint destruction in rheumatoid arthritis (RA). Gadd45β (growth arrest and DNA damage inducible gene), which is an NF-κB regulated gene, was recently identified as an endo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Svensson, Camilla I., Inoue, Tomoyuki, Hammaker, Deepa, Fukushima, Akihisa, Papa, Salvatore, Franzoso, Guido, Schett, Georg, Corr, Maripat, Boyle, David L., Firestein, Gary S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858378/
https://ncbi.nlm.nih.gov/pubmed/19877043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24887
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg