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Kinetic analysis of synovial signaling and gene expression in animal models of arthritis

OBJECTIVES: Animal models of arthritis are frequently used to evaluate novel therapeutic agents. However, their ability to predict responses in humans is variable. We examined the time course of signaling molecule and gene expression in two models of arthritis to assist with selection of the model a...

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Detalhes bibliográficos
Main Authors: Fukushima, Akihisa, Boyle, David L, Corr, Maripat, Firestein, Gary S
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859101/
https://ncbi.nlm.nih.gov/pubmed/19473996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2009.112201
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