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Selenium Supplementation Fails to Correct the Selenoprotein Synthesis Defect in Subjects with SBP2 Gene Mutations

BACKGROUND: Selenium (Se) is an essential trace element needed for the biosynthesis of selenoproteins. Selenocysteine incorporation sequence binding protein 2 (SBP2) represents a key trans-acting factor for the co-translational insertion of selenocysteine into selenoproteins. We recently described c...

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Detalhes bibliográficos
Main Authors: Schomburg, Lutz, Dumitrescu, Alexandra M., Liao, Xiao-Hui, Bin-Abbas, Bassam, Hoeflich, Johanna, Köhrle, Josef, Refetoff, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858371/
https://ncbi.nlm.nih.gov/pubmed/19265499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2008.0397
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