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Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues.
Selenoprotein P (SePP), the major selenoprotein in plasma, has been implicated in selenium transport, selenium detoxification or antioxidant defence. We generated SePP-knockout mice that were viable, but exhibited reduced growth and developed ataxia. Selenium content was elevated in liver, but low i...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223208/ https://ncbi.nlm.nih.gov/pubmed/12521380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021853 |
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