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Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply
Liver-specific inactivation of Trsp, the gene for selenocysteine tRNA, removes SePP (selenoprotein P) from plasma, causing serum selenium levels to fall from 298 μg/l to 50 μg/l and kidney selenium to decrease to 36% of wild-type levels. Likewise, glutathione peroxidase activities decreased in plasm...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134785/ https://ncbi.nlm.nih.gov/pubmed/15638810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041973 |
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