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Invader LNA – Efficient Targeting of Short Double Stranded DNA
Despite progress with triplex-forming oligonucleotides or helix-invading peptide nucleic acids (PNAs), there remains a need for probes facilitating sequence-unrestricted targeting of double stranded DNA (dsDNA) at physiologically relevant conditions. Invader LNA probes, i.e., DNA duplexes with “+1 i...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858348/ https://ncbi.nlm.nih.gov/pubmed/20401378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b923465a |
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