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HPV16 E6 confers p53-dependent and p53-independent phenotypes in the epidermis of mice deficient for E6AP

High-risk human papillomaviruses are the causative agents of cervical and other anogenital cancers. In these cancers, two viral oncogenes, E6 and E7, are expressed. E6 is best known for its ability to inactivate the tumor suppressor p53, which is thought to arise through ubiquitin-mediated degradati...

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Bibliografische gegevens
Hoofdauteurs: Shai, A, Nguyen, ML, Wagstaff, J, Jiang, Y-h, Lambert, PF
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858288/
https://ncbi.nlm.nih.gov/pubmed/17130828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210130
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