Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

BACKGROUND: Mitochondrial function is impaired in Parkinson's disease (PD) and may contribute to the pathogenesis of PD, but the causes of mitochondrial impairment in PD are unknown. Mitochondrial dysfunction is recapitulated in cell lines expressing mitochondrial DNA (mtDNA) from PD patients,...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Simon, David K, Pankratz, Nathan, Kissell, Diane K, Pauciulo, Michael W, Halter, Cheryl A, Rudolph, Alice, Pfeiffer, Ronald F, Nichols, William C, Foroud, Tatiana
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858137/
https://ncbi.nlm.nih.gov/pubmed/20356410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-53
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