Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

BACKGROUND: Mitochondrial function is impaired in Parkinson's disease (PD) and may contribute to the pathogenesis of PD, but the causes of mitochondrial impairment in PD are unknown. Mitochondrial dysfunction is recapitulated in cell lines expressing mitochondrial DNA (mtDNA) from PD patients,...

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Bibliografske podrobnosti
Main Authors: Simon, David K, Pankratz, Nathan, Kissell, Diane K, Pauciulo, Michael W, Halter, Cheryl A, Rudolph, Alice, Pfeiffer, Ronald F, Nichols, William C, Foroud, Tatiana
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858137/
https://ncbi.nlm.nih.gov/pubmed/20356410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-53
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