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Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

BACKGROUND: Mitochondrial function is impaired in Parkinson's disease (PD) and may contribute to the pathogenesis of PD, but the causes of mitochondrial impairment in PD are unknown. Mitochondrial dysfunction is recapitulated in cell lines expressing mitochondrial DNA (mtDNA) from PD patients,...

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Bibliografische gegevens
Hoofdauteurs: Simon, David K, Pankratz, Nathan, Kissell, Diane K, Pauciulo, Michael W, Halter, Cheryl A, Rudolph, Alice, Pfeiffer, Ronald F, Nichols, William C, Foroud, Tatiana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858137/
https://ncbi.nlm.nih.gov/pubmed/20356410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-53
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