Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

BACKGROUND: Mitochondrial function is impaired in Parkinson's disease (PD) and may contribute to the pathogenesis of PD, but the causes of mitochondrial impairment in PD are unknown. Mitochondrial dysfunction is recapitulated in cell lines expressing mitochondrial DNA (mtDNA) from PD patients,...

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Main Authors: Simon, David K, Pankratz, Nathan, Kissell, Diane K, Pauciulo, Michael W, Halter, Cheryl A, Rudolph, Alice, Pfeiffer, Ronald F, Nichols, William C, Foroud, Tatiana
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858137/
https://ncbi.nlm.nih.gov/pubmed/20356410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-53
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