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Viral nanoparticles associate with regions of inflammation and blood brain barrier disruption during CNS infection

Targeted treatment of inflammatory diseases of the central nervous system (CNS) remains problematic due to the complex pathogenesis of these disorders and difficulty in drug delivery. The plant virus, cow pea mosaic virus (CPMV), has recently been explored as a nanoparticle delivery system for thera...

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Detalhes bibliográficos
Main Authors: Shriver, Leah P., Koudelka, Kristopher J., Manchester, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858070/
https://ncbi.nlm.nih.gov/pubmed/19394707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.03.015
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