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Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization
Wnt/β-catenin signalling controls cell fates in development, tissue homeostasis and cancer. Wnt binding to Frizzled receptors triggers recruitment of Dishevelled to the plasma membrane and formation of a signalosome containing the LRP5/6 co-receptor, whose cytoplasmic tail (ctail) thus becomes phosp...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858023/ https://ncbi.nlm.nih.gov/pubmed/20388731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.067546 |
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