Variants in ASK1 Are Associated With Skeletal Muscle ASK1 Expression, In Vivo Insulin Resistance, and Type 2 Diabetes in Pima Indians

OBJECTIVE: Prior genome-wide association and exon array expression studies both provided suggestive evidence that apoptosis signal regulating kinase 1 (ASK1) may influence in vivo insulin action in Pima Indians. Genetic variants in or near ASK1 were analyzed to assess the role of this gene in insuli...

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Hlavní autoři: Bian, Li, Hanson, Robert L., Ossowski, Victoria, Wiedrich, Kim, Mason, Clinton C., Traurig, Michael, Muller, Yunhua L., Kobes, Sayuko, Knowler, William C., Baier, Leslie J., Bogardus, Clifton
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857909/
https://ncbi.nlm.nih.gov/pubmed/20185809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1700
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