SIRT1 is Associated with a Decrease in Acute Insulin Secretion and a Sex Specific Increase in Risk for Type 2 Diabetes in Pima Indians

Genetic variation in SIRT1 affects obesity-related phenotypes in several populations. The purpose of this study was to determine whether variation in SIRT1 affects susceptibility to obesity or type 2 diabetes in Pima Indians, a population with very high prevalence and incidence rates of these diseas...

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Detalhes bibliográficos
Main Authors: Dong, Yan, Guo, Tingwei, Traurig, Michael, Mason, Clint C., Kobes, Sayuko, Perez, Jessica, Knowler, William C., Bogardus, Clifton, Hanson, Robert L., Baier, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224181/
https://ncbi.nlm.nih.gov/pubmed/21871827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.08.001
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