Association Analyses of Variants in the DIO2 Gene with Early-Onset Type 2 Diabetes Mellitus in Pima Indians

BACKGROUND: The type 2 deiodinase gene (DIO2) encodes a deiodinase that converts the thyroid prohormone, thyroxine, to the biologically active triiodothyronine. Thyroid hormones regulate energy balance and may also influence glucose metabolism. Therefore, we hypothesized that variations in DIO2 coul...

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Hlavní autoři: Nair, Saraswathy, Muller, Yunhua Li, Ortega, Emilio, Kobes, Sayuko, Bogardus, Clifton, Baier, Leslie J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247704/
https://ncbi.nlm.nih.gov/pubmed/22142372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.0455
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